Robotic Microtool Control in an Intelligent Automated in Vitro Fertilization And Intracytoplasmic Sperm Injection Platform
Mendizabal-Ruiz et al. | Patent No. US 12,245,793 B2
Disclosed is a method of artificial intelligence-based robotic pipetting for cell preparation. The method includes training an artificial intelligence/machine learning system (AI/ML system) to classify images of biological specimens. The method includes storing the classified images. The method includes receiving an image object from an imaging system that includes a microscopy system, a camera system con-figured to receive imaging from the microscopy system, and a lighting system configured to illuminate a biological material. The method includes processing the image object, using the AJ/ML system to determine a presence of a retrievable target cell. The method includes positioning a robotic pipettor at a target physical orientation relative to the retrievable target cell. The method includes confirming the robotic pipettor’s location at the target physical orientation, using AI/ML system. The method includes instructing the robotic pipettor to obtain the retrievable target cell from the target physical orientation.
